Doré C, Hesp R, Wilkins D, Garrow J S
Hum Nutr Clin Nutr. 1982;36C(1):41-8.
A regression analysis was made of resting metabolic rate on weight and body composition in 140 women with varying degrees of obesity. In 19 severely obese women before weight loss, average resting metabolic rate was 290 ml O2/min, or 4 per cent higher than predicted from the regression equation. After losing 30 kg in one year the average metabolic rate of this group was 234 ml O2/min, 1 per cent higher than that predicted for their reduced weight. Women whose metabolic rate was high or low relative to prediction before weight loss tended to maintain this status after weight loss (P less than 0.05). There is a close relation between resting metabolic rate and total energy expenditure. We conclude that there is a reduction in energy requirements for weight maintenance after massive weight loss, but the requirements of obese patients after weight loss are similar to those of people of comparable weight who have not reduced.
对140名不同肥胖程度的女性的静息代谢率与体重及身体组成进行了回归分析。在19名体重减轻前的重度肥胖女性中，平均静息代谢率为290毫升氧气/分钟，比根据回归方程预测的数值高4%。在一年内减重30千克后，该组的平均代谢率为234毫升氧气/分钟，比根据其减轻后的体重预测的数值高1%。在体重减轻前，代谢率相对于预测值较高或较低的女性，在体重减轻后往往保持这种状态（P小于0.05）。静息代谢率与总能量消耗之间存在密切关系。我们得出结论，大量减重后维持体重所需的能量需求降低，但肥胖患者减重后的需求与未减重的同等体重人群相似。
