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抑制非洲爪蟾幼体晶状体再生。

Inhibition of lens regeneration in larval Xenopus laevis.

作者信息

Cioni C, Filoni S, Bosco L

出版信息

J Exp Zool. 1982 Mar 1;220(1):103-8. doi: 10.1002/jez.1402200113.

DOI:10.1002/jez.1402200113
PMID:7077262
Abstract

The present research aims at showing the role played by the lens in inhibiting lens-forming transformations of the outer cornea of Xenopus laevis tadpoles. Two types of experiment were carried out: 1) lentectomy and insertion of a Millipore filter disk at the side of the lens, and 2) lentectomy and insertion of a Millipore disk with a central hole. Results indicate that when the lens is replaced by a mechanical obstacle capable of preventing direct communication between vitreous and anterior chambers, definite inhibition of the lens-forming transformations of the outer cornea occurs. These data strongly suggest that the inhibition exerted by the lens on lens-forming transformations of the outer cornea in Xenopus laevis eyes is mechanical rather than chemical in nature.

摘要

本研究旨在揭示晶状体在抑制非洲爪蟾蝌蚪外角膜形成晶状体转化过程中所起的作用。进行了两种类型的实验:1)晶状体切除术并在晶状体一侧插入微孔滤膜盘,以及2)晶状体切除术并插入带有中心孔的微孔盘。结果表明,当晶状体被能够阻止玻璃体与前房直接连通的机械障碍物取代时,外角膜的晶状体形成转化会受到明确的抑制。这些数据有力地表明,晶状体对非洲爪蟾眼睛外角膜晶状体形成转化的抑制本质上是机械性的而非化学性的。

相似文献

1
Inhibition of lens regeneration in larval Xenopus laevis.抑制非洲爪蟾幼体晶状体再生。
J Exp Zool. 1982 Mar 1;220(1):103-8. doi: 10.1002/jez.1402200113.
2
Lens formation from cornea in the presence of the old lens in larval Xenopus laevis.在非洲爪蟾幼体中,旧晶状体存在的情况下角膜形成晶状体。
J Exp Zool. 1980 Jul;213(1):9-14. doi: 10.1002/jez.1402130103.
3
Relationships between eye factors and lens-forming transformations in the cornea and pericorneal epidermis of larval Xenopus laevis.非洲爪蟾幼体角膜和角膜周围表皮中眼因素与晶状体形成转变之间的关系。
J Exp Zool. 1979 Aug;209(2):261-82. doi: 10.1002/jez.1402090208.
4
Experimental analysis of lens-forming capacity in Xenopus borealis larvae.北方爪蟾幼虫晶状体形成能力的实验分析。
J Exp Zool A Comp Exp Biol. 2006 Jul 1;305(7):538-50. doi: 10.1002/jez.a.297.
5
Lens regeneration in larval Xenopus laevis: experimental analysis of the decline in the regenerative capacity during development.非洲爪蟾幼体晶状体再生:发育过程中再生能力下降的实验分析
Dev Biol. 1997 Jul 1;187(1):13-24. doi: 10.1006/dbio.1997.8598.
6
Experimental analysis of the lens-forming competence of the cornea, iris, and retina in Xenopus laevis tadpoles.非洲爪蟾蝌蚪角膜、虹膜和视网膜晶状体形成能力的实验分析。
J Exp Zool. 1981 May;216(2):267-76. doi: 10.1002/jez.1402160207.
7
Cornea-lens transdifferentiation in the anuran, Xenopus tropicalis.非洲爪蟾(热带爪蟾)中的角膜-晶状体转分化
Dev Genes Evol. 2001 Sep;211(8-9):377-87. doi: 10.1007/s004270100163.
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Eye factors and lens-forming transformations of outer cornea in Xenopus laevis larvae.非洲爪蟾幼体的眼部因素及外角膜的晶状体形成转变
J Exp Zool. 1986 Dec;240(3):401-7. doi: 10.1002/jez.1402400315.
9
Lens regeneration from cornea of larval Xenopus laevis in the presence of the lens.在晶状体存在的情况下,从非洲爪蟾幼体的角膜进行晶状体再生。
J Embryol Exp Morphol. 1978 Dec;48:205-14.
10
Secondary lens formation from the cornea following implantation of larval tissues between the inner and outer corneas of Xenopus laevis tadpoles.在非洲爪蟾蝌蚪的内角膜和外角膜之间植入幼虫组织后,角膜形成次生晶状体。
J Embryol Exp Morphol. 1981 Aug;64:121-32.

引用本文的文献

1
Molecular and cellular aspects of amphibian lens regeneration.两栖类晶状体再生的分子与细胞层面
Prog Retin Eye Res. 2010 Nov;29(6):543-55. doi: 10.1016/j.preteyeres.2010.07.002. Epub 2010 Jul 16.
2
The lens-regenerating competence in the outer cornea and epidermis of larval Xenopus laevis is related to pax6 expression.非洲爪蟾幼体的角膜外层和表皮中的晶状体再生能力与paired box 6(pax6)基因的表达有关。
J Anat. 2008 May;212(5):612-20. doi: 10.1111/j.1469-7580.2008.00891.x.