Mansfield L E, Stein M R
Ann Allergy. 1978 Oct;41(4):224-6.
Fifteen asthmatic patients with gastroesophageal reflux underwent an intraesophageal acid provocation test. Pulmonary function measurements demonstrated increased flow resistance when reflux symptoms occurred. After relief of symptoms, these changes tended to rapidly reverse. The technique employed and the prompt reversal of pulmonary functions suggest reflex mechanisms may be producing the observed bronchoconstriction.
15名患有胃食管反流的哮喘患者接受了食管内酸激发试验。肺功能测量结果显示，反流症状出现时气流阻力增加。症状缓解后，这些变化往往迅速逆转。所采用的技术以及肺功能的迅速逆转表明，反射机制可能导致了所观察到的支气管收缩。
