Naeye R L, Peters E C
Pediatrics. 1982 Jun;69(6):724-7.
In order to determine whether pregnancy outcome was altered when women were employed outside their homes, 7,722 pregnancies were analyzed. Gestations were not shortened but newborns of women who worked in the third trimester weighed 150 to 400 gm less than newborns of mothers who remained at home. The growth retardation was greatest when women were underweight pregravid and had a low pregnancy weight gain, when they were hypertensive, or when the work required standing. The growth retardation remained after the data were stratified by race, socioeconomic status, and other maternal factors that commonly influence fetal growth. The frequency of large placental infarcts progressively increased when women continued stand-up work into late gestation. Such infarcts reached a peak of 250/1,000 births after the 37th week of gestation in stand-up workers. Low uteroplacental blood flow is a likely explanation for both the fetal growth retardation and the large placental infarcts.
为了确定外出工作的女性其妊娠结局是否会发生改变，对7722例妊娠进行了分析。妊娠期并未缩短，但妊娠晚期工作的女性所生新生儿比居家母亲所生新生儿体重轻150至400克。当女性孕前体重过轻且孕期体重增加较少、患有高血压或工作需要站立时，生长发育迟缓最为明显。在按种族、社会经济地位和其他通常影响胎儿生长的母体因素对数据进行分层后，生长发育迟缓现象依然存在。当女性在妊娠晚期继续从事站立工作时，大面积胎盘梗死的发生率逐渐增加。在站立工作的女性中，此类梗死在妊娠第37周后达到每1000例分娩250例的峰值。子宫胎盘血流不足可能是胎儿生长发育迟缓和大面积胎盘梗死的一个原因。
