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[E型肉毒中毒。两例近期病例(作者译)]

[Type E botulism. Two recent cases (author's transl)].

作者信息

Blettery B, Soichot P, Virot C, Lorcerie B, Hillon P

出版信息

Nouv Presse Med. 1982 Apr 3;11(15):1131-3.

PMID:7079135
Abstract

Two brothers, aged 29 and 31, developed severe type E botulism 12 hours after eating salted herrings. The younger died rapidly, the other survived after treatment with type E botulinus antitoxin under intensive care. Limited electromyographic exploration of the surviving patient showed characteristic signs of presynaptic block. This method may be helpful in the diagnosis of atypical forms of the disease. Type E botulism is uncommon in France. It is almost exclusively transmitted by raw, smoked or salted fish and, for some obscure reason, rarely affects all those who shared the same meal. Contrary to types A and B botulism, it usually responds to its specific antitoxin, which must be administered as early as possible. The other therapeutic measures (tracheostomy, controlled ventilation, tube feeding) are the same for all types.

摘要

两名分别为29岁和31岁的兄弟,在食用咸鱼12小时后患上了严重的E型肉毒中毒。弟弟很快死亡,另一名在重症监护下接受E型肉毒抗毒素治疗后存活。对存活患者进行的有限肌电图检查显示出突触前阻滞的特征性迹象。这种方法可能有助于诊断该病的非典型形式。E型肉毒中毒在法国并不常见。它几乎完全通过生的、烟熏或腌制的鱼类传播,并且由于某些不明原因,很少影响所有共享同一餐食的人。与A型和B型肉毒中毒不同,它通常对其特异性抗毒素有反应,必须尽早给药。其他治疗措施(气管切开术、控制通气、管饲)对所有类型都是相同的。

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