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肉毒中毒的轻症病程(作者译)

[Mild course of botulinus intoxication (author's transl)].

作者信息

Richert S, Hagenah R, Müller-Jensen A

出版信息

Dtsch Med Wochenschr. 1975 Nov 14;100(46):2394-7. doi: 10.1055/s-0028-1106554.

DOI:10.1055/s-0028-1106554
PMID:1183348
Abstract

Botulinus poisoning generally ends fatally after an only short course, mild forms being rare. In four members of a family who had eaten deep-frozen grilled sausages symptoms of botulinus poisoning developed, predominantly marked by disturbances of the autonomic nervous system. The course was so mild that hospitalization was not necessary nor was specific antitoxin administration. All clinical symptoms had disappeared after nine weeks. But special clinical and neurophysiological studies (electromyography, pupillography, electroencephalography) demonstrated abnormalities for very much longer. Botulinus poisoning was proven in animal tests and neutralization tests with botulinus antitoxin. The epidemiology, source of infection, and clinical symptoms suggest botulinus type B poisoning.

摘要

肉毒中毒通常病程短暂,最终多以死亡告终,轻症极为罕见。有一家四口食用了速冻烤肠后出现肉毒中毒症状,主要表现为自主神经系统紊乱。病程极为轻微,无需住院,也未进行特异性抗毒素治疗。九周后所有临床症状均消失。但特殊的临床和神经生理学检查(肌电图、瞳孔描记法、脑电图)显示异常持续了更长时间。动物试验及肉毒抗毒素中和试验证实为肉毒中毒。从流行病学、感染源及临床症状来看,提示为B型肉毒中毒。

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[Mild course of botulinus intoxication (author's transl)].肉毒中毒的轻症病程(作者译)
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引用本文的文献

1
Botulism: clinical neurophysical findings.肉毒中毒:临床神经物理学检查结果
J Neurol. 1978 Feb 14;217(3):159-71. doi: 10.1007/BF00312957.