Rotschafer J C, Crossley K B, Lesar T S, Zaske D, Miller K
Antimicrob Agents Chemother. 1982 Jan;21(1):170-2. doi: 10.1128/AAC.21.1.170.
Pharmacokinetic parameters of cefaclor were studied in eight patients after an oral dose of 250 mg. Serum samples were obtained before and on 19 occasions after oral administration. Cefaclor serum concentrations were determined by a new high-performance liquid chromatographic technique.
在8名患者口服250毫克头孢克洛后研究了其药代动力学参数。在口服给药前及给药后的19个时间点采集血清样本。采用一种新的高效液相色谱技术测定头孢克洛的血清浓度。