Duve H, Thorpe A, Lazarus N R, Lowry P J
Biochem J. 1982 Feb 1;201(2):429-32. doi: 10.1042/bj2010429.
A neuropeptide purified from the brain of the blowfly (Calliphora vomitoria) that cross-reacts in a bovine pancreatic polypeptide radioimmunoassay has been subjected to amino acid analysis. The amino acid composition of the peptide shows homology with vertebrate pancreatic polypeptide species. Amounts of the neuropeptide calculated from amino acid analysis record with those measured by the pancreatic polypeptide radioimmunoassay. These results suggest that the primary structure of the Calliphora neuropeptide is very similar to that of mammalian pancreatic polypeptides.
从绿头苍蝇(红头丽蝇)大脑中纯化出的一种神经肽,在牛胰多肽放射免疫测定中会发生交叉反应,现已对其进行了氨基酸分析。该肽的氨基酸组成显示出与脊椎动物胰多肽种类具有同源性。通过氨基酸分析计算得出的神经肽含量与通过胰多肽放射免疫测定法测得的结果相符。这些结果表明,红头丽蝇神经肽的一级结构与哺乳动物胰多肽的一级结构非常相似。