Gatsko G G, Mazhul' L M, Pozdniakova E A
Biull Eksp Biol Med. 1982 Apr;93(4):30-2.
Experiments on male rats aged 4-6 and 24-26 months have shown that the concentration of malonic dialdehyde (MDA) increases with aging. Forty-eight-hour fasting lowers the MDA content in all the samples examined (blood serum, liver, adipose tissue) of old rats. No changes have been found in young rats. It is suggested that retardation of lipid peroxidation caused by fasting might be associated with antioxidative system activation.
对4至6个月龄和24至26个月龄雄性大鼠进行的实验表明,丙二醛(MDA)浓度会随着衰老而增加。禁食48小时可降低老年大鼠所有检测样本(血清、肝脏、脂肪组织)中的MDA含量。在年轻大鼠中未发现变化。提示禁食引起的脂质过氧化作用的延缓可能与抗氧化系统的激活有关。