由于细胞ATP含量降低及多种药物的作用，原代培养的大鼠肝细胞对甲状腺素（T4）、3,3',5-三碘甲状腺原氨酸（T3）和3,3',5'-三碘甲状腺原氨酸（反T3）的转运减少。 - Suppr

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超能文献

Decreased transport of thyroxine (T4), 3,3',5-triiodothyronine (T3) and 3,3',5'-triiodothyronine (rT3) into rat hepatocytes in primary culture due to a decrease of cellular ATP content and various drugs.

作者信息

Krenning E P, Docter R, Bernard B, Visser T, Hennemann G

出版信息

FEBS Lett. 1982 Apr 19;140(2):229-33. doi: 10.1016/0014-5793(82)80900-9.

DOI:10.1016/0014-5793(82)80900-9

PMID:7084465

Abstract

摘要

相似文献

Decreased transport of thyroxine (T4), 3,3',5-triiodothyronine (T3) and 3,3',5'-triiodothyronine (rT3) into rat hepatocytes in primary culture due to a decrease of cellular ATP content and various drugs.由于细胞ATP含量降低及多种药物的作用，原代培养的大鼠肝细胞对甲状腺素（T4）、3,3',5-三碘甲状腺原氨酸（T3）和3,3',5'-三碘甲状腺原氨酸（反T3）的转运减少。

FEBS Lett. 1982 Apr 19;140(2):229-33. doi: 10.1016/0014-5793(82)80900-9.

Thyroxine, 3,5,3'-triiodothyronine, and 3,3',5'-triiodothyronine concentrations in several tissues of the rat: effects of amiodarone and desethylamiodarone on thyroid hormone metabolism [corrected].大鼠多个组织中甲状腺素、3,5,3'-三碘甲状腺原氨酸和3,3',5'-三碘甲状腺原氨酸的浓度：胺碘酮和去乙胺碘酮对甲状腺激素代谢的影响[校正后]

Endocrinology. 1990 Oct;127(4):1656-64. doi: 10.1210/endo-127-4-1656.

Transport and metabolism of iodothyronines in cultured human hepatocytes.

J Clin Endocrinol Metab. 1993 Jul;77(1):139-43. doi: 10.1210/jcem.77.1.8392080.

Rat placenta is an active site of inner ring deiodination of thyroxine and 3,3',5-triiodothyronine.大鼠胎盘是甲状腺素和3,3',5-三碘甲状腺原氨酸内环脱碘的活跃部位。

Endocrinology. 1982 Jan;110(1):34-7. doi: 10.1210/endo-110-1-34.

Impaired thyroxine and 3,5,3'-triiodothyronine handling by rat hepatocytes in the presence of serum of patients with nonthyroidal illness.在非甲状腺疾病患者血清存在的情况下，大鼠肝细胞对甲状腺素和3,5,3'-三碘甲状腺原氨酸的处理受损。

J Clin Endocrinol Metab. 1995 Aug;80(8):2364-70. doi: 10.1210/jcem.80.8.7629231.

Amiodarone inhibits the conversion of thyroxine to triiodothyronine in isolated rat hepatocytes.胺碘酮在离体大鼠肝细胞中抑制甲状腺素向三碘甲状腺原氨酸的转化。

Endocrinology. 1984 Oct;115(4):1605-8. doi: 10.1210/endo-115-4-1605.

In vivo and in vitro effects of adrenaline on conversion of thyroxine to triiodothyronine and to reverse-triiodothyronine in dog liver and heart.

Eur J Clin Invest. 1980 Jun;10(3):189-92. doi: 10.1111/j.1365-2362.1980.tb00019.x.

Brain cortex reverse triiodothyronine (rT3) and triiodothyronine concentrations under steady state infusions of thyroxine and rT3.在甲状腺素和反三碘甲状腺原氨酸稳态输注情况下脑皮质中的反三碘甲状腺原氨酸（rT3）和三碘甲状腺原氨酸浓度。

Endocrinology. 1987 Apr;120(4):1590-6. doi: 10.1210/endo-120-4-1590.

Sequential deiodination of thyroxine to 3,3'-diiodothyronine via 3,5,3'-triiodothyronine and 3,3',5'-triiodothyronine in rat liver homogenate. The effects of fasting versus glucose feeding.甲状腺素在大鼠肝脏匀浆中依次经3,5,3'-三碘甲状腺原氨酸和3,3',5'-三碘甲状腺原氨酸脱碘生成3,3'-二碘甲状腺原氨酸。禁食与葡萄糖喂养的影响。

J Biol Chem. 1980 Jan 10;255(1):49-54.

Subcellular localization of thyroxine and reverse triiodothyronine outer ring monodeiodinating activities.

Endocrinology. 1979 Feb;104(2):365-71. doi: 10.1210/endo-104-2-365.

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Amiodarone and thyroid physiology, pathophysiology, diagnosis and management.胺碘酮与甲状腺生理学、病理生理学、诊断与治疗。

Trends Cardiovasc Med. 2019 Jul;29(5):285-295. doi: 10.1016/j.tcm.2018.09.005. Epub 2018 Sep 20.

Amiodarone-induced thyrotoxic thyroiditis: a diagnostic and therapeutic challenge.胺碘酮所致甲状腺毒症性甲状腺炎：诊断与治疗挑战

Case Rep Med. 2014;2014:231651. doi: 10.1155/2014/231651. Epub 2014 Nov 12.

Inhibition of the type 2 iodothyronine deiodinase underlies the elevated plasma TSH associated with amiodarone treatment.胺碘酮治疗导致血浆 TSH 升高的基础是 2 型甲状腺素脱碘酶的抑制。

Endocrinology. 2010 Dec;151(12):5961-70. doi: 10.1210/en.2010-0553. Epub 2010 Oct 6.

Effects of amiodarone administration during pregnancy on neonatal thyroid function and subsequent neurodevelopment.孕期使用胺碘酮对新生儿甲状腺功能及后续神经发育的影响。

J Endocrinol Invest. 2001 Feb;24(2):116-30. doi: 10.1007/BF03343825.

Evidence that the uptake of tri-iodo-L-thyronine by human erythrocytes is carrier-mediated but not energy-dependent.有证据表明，人红细胞对三碘-L-甲状腺原氨酸的摄取是由载体介导的，但不依赖能量。

Biochem J. 1982 Oct 15;208(1):27-34. doi: 10.1042/bj2080027.

Plasma membrane transport of thyroid hormone: its possible pathophysiological significance.甲状腺激素的质膜转运：其可能的病理生理意义。

J Endocrinol Invest. 1983 Feb;6(1):59-66. doi: 10.1007/BF03350563.

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