Bordia A
Atherosclerosis. 1978 Aug;30(4):355-60. doi: 10.1016/0021-9150(78)90129-6.
In 6 healthy adults the effect of essential oil of garlic on platelet aggregation was studied in vitro with an aggreganometer. The blood was collected in a siliconized centrifuge tube containing sodium citrate. The aggregating agents used were ADP, epinephrine and collagen. In each subject aggregation was studied 3 times: (i) initial fasting control; (ii) immediately after (i) but with essential oil of garlic drawn into the syringe together with the sodium citrate; (iii) 5 days after feeding 0.5 mg of essential oil of garlic daily. Addition of essential oil of garlic inhibited in-vitro platelet aggregation induced by ADP, epinephrine or collagen; the effect was dose-related. Oral administration of garlic also decreased platelet aggregation. Thus, garlic seems to inhibit some aspects of thrombus formation.
在6名健康成年人中，使用血小板聚集仪在体外研究了大蒜精油对血小板聚集的影响。血液采集于含有柠檬酸钠的硅化离心管中。使用的聚集剂为二磷酸腺苷（ADP）、肾上腺素和胶原蛋白。对每名受试者的聚集情况进行了3次研究：（i）初始空腹对照；（ii）在（i）之后立即进行，但将大蒜精油与柠檬酸钠一起吸入注射器；（iii）每天喂食0.5毫克大蒜精油5天后。添加大蒜精油可抑制由ADP、肾上腺素或胶原蛋白诱导的体外血小板聚集；该效应与剂量相关。口服大蒜也可降低血小板聚集。因此，大蒜似乎能抑制血栓形成的某些方面。
