Wright B E, Bird A C, Hamilton A M
Br J Ophthalmol. 1978 Sep;62(9):609-21. doi: 10.1136/bjo.62.9.609.
Twenty-six patients are described who suffered from acute bilateral multifocal pigment epithelial disease. In 7 the pattern of disease was indistinguishable from acute posterior multifocal placoid pigment epitheliopathy, while in 8 it was indistinguishable from Harada's disease. In a further 9 cases the pigment epithelial disease was associated with serious detachment of the retina simulating Harada's disease but without systemic symptoms; spontaneous resolution occurred within a few days, and there was no recurrence. One additional case had short-lived disease with detachment initially, but this was followed by severe recurrence, and the last patient had serious detachment in 1 eye but not the other. When seen as a whole these patients appeared to represent a continuous spectrum of disease making it difficult to define boundaries between one condition and another. The difficulties in distinguishing diseases according to morphology alone are emphasised.
本文描述了26例患有急性双侧多灶性色素上皮疾病的患者。其中7例疾病模式与急性后极部多灶性扁平色素上皮病变无法区分，8例与原田病无法区分。另外9例色素上皮疾病与类似原田病的严重视网膜脱离相关，但无全身症状；数天内自发消退，且无复发。另有1例最初有短暂性疾病伴视网膜脱离，但随后出现严重复发，最后1例患者1只眼有严重视网膜脱离，另1只眼则没有。总体来看，这些患者似乎代表了一系列连续的疾病，难以界定一种疾病与另一种疾病之间的界限。强调了仅根据形态学区分疾病的困难。
