Uptake of [3H]serotonin and [3H]noradrenaline in the raphe nuclei and the locus coeruleus of C57BL/6 Rholco and BALB/c Cenlco mice at three times of the day.

Uptake of [3H]serotonin (5-HT) and [3H]noradrenaline (NA) in the raphe nuclei and the locus coeruleus of C57BL/6 and BALB/c mice has been analysed at 3 times of the day. Daily mean results clearly show a higher uptake of [3H]5-HT and [3H]NA in the raphe dorsalis of the BALB/c strain than in C57BL/6. A higher uptake of [3H]NA is also found in the locus coeruleus of BALB/c mice than in C57BL/6. However, differences between the strains are neither visible at all times of the day nor simultaneously in the different structures.