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[太空飞行中的人工重力对神经组织结构中水溶性蛋白质浓度的影响]

[Effect of artificial gravitational force in space flight on the concentration of water soluble proteins in nerve tissue structures].

作者信息

Gorbunova A V, Portugalov V V

出版信息

Biull Eksp Biol Med. 1978 Oct;86(10):421-4.

PMID:708869
Abstract

The content of water-soluble proteins in the grey and white matter of the spinal cord, spinal ganglia, and the sensory-motor area of the large hemispheres of the brain of rats after a 18.5-day space flight was measured. The content of water-soluble proteins in the grey and white matter of the spinal cord and spinal ganglia of rats exposed to weightlessness showed a significant decrease 4.5--9.5 hours postflight. The water-soluble protein content in the white matter of the spinal cord diminished in rats exposed to artificial gravity inflight. The water-soluble proteins content in the grey matter of the spinal cord of rats exposed to weightlessness increased significantly 25 days postflight. The content of water-soluble proteins in the grey matter of the cortex of the sensory-motor area of the large hemispheres of the brain of rats exposed to weightlessness and artificial gravity remained unchanged in comparison with the vivarium controls both 4.5--9.5 hours and 25 days postflight.

摘要

对大鼠进行18.5天太空飞行后,测定其脊髓、脊髓神经节以及大脑大半球感觉运动区灰质和白质中水溶性蛋白质的含量。暴露于失重环境的大鼠,在飞行后4.5 - 9.5小时,脊髓和脊髓神经节灰质和白质中水溶性蛋白质含量显著降低。在飞行中暴露于人工重力的大鼠,脊髓白质中水溶性蛋白质含量减少。暴露于失重环境的大鼠,在飞行后25天,脊髓灰质中水溶性蛋白质含量显著增加。与饲养对照相比,暴露于失重和人工重力环境的大鼠,在飞行后4.5 - 9.5小时以及25天,大脑大半球感觉运动区皮质灰质中水溶性蛋白质含量均未发生变化。

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