Gorbunova A V, Portugalov V V
Aviat Space Environ Med. 1976 Jul;47(7):708-10.
The content of RNA and cytoplasmic protein was assayed by methods of quantitative cytochemistry in motoneurons of anterior horns of the spinal cord and neurons of spinal ganglia of rats flown for 22 d. It was shown that the 22-d space flight did not change the RNA content in motoneurons of anterior horns of the spinal cord and reduced the RNA content in large neurons of spinal ganglia. The protein content in the cytoplasm of motoneurons and neurons of spinal ganglia was significantly lowered as compared with the control. The RNA content 27 d postflight in motoneurons of anterior horns of the spinal cord was significantly reduced and in neurons of spinal ganglia it did not differ from the control. On the 27th postflight day the protein content in the cytoplasm of motoneurons returned to the preflight level and in the cytoplasm of large neurons of spinal ganglia remained lowered.
采用定量细胞化学方法，对飞行22天的大鼠脊髓前角运动神经元和脊神经节神经元中的RNA及细胞质蛋白含量进行了测定。结果显示，22天的太空飞行并未改变脊髓前角运动神经元中的RNA含量，但降低了脊神经节大神经元中的RNA含量。与对照组相比，运动神经元和脊神经节神经元细胞质中的蛋白含量显著降低。飞行后27天，脊髓前角运动神经元中的RNA含量显著降低，而脊神经节神经元中的RNA含量与对照组无差异。飞行后第27天，运动神经元细胞质中的蛋白含量恢复到飞行前水平，而脊神经节大神经元细胞质中的蛋白含量仍较低。
