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[太空飞行对大鼠脊髓和椎间神经节可溶性蛋白质组成的影响]

[Effect of space flight on the makeup of the soluble proteins of the spinal cord and intervertebral ganglia of rats].

作者信息

Gorbunova A V, Portugalov V V

出版信息

Biull Eksp Biol Med. 1977 Aug;84(8):168-71.

PMID:907819
Abstract

The content of individual protein fractions extracted successively from the spinal cord (at the level of the lumbar enlargement and the spinal ganglia) with distilled water, 0.85% NaCl solution and 0.1 N NaOH was studied. The content of water-soluble proteins in the white and grey matter of the spinal cord decreased significantly 12 hours postflight. The content of salt-soluble and alkali-soluble proteins in the spinal cord and spinal ganglia structures per 1 mg of fresh tissue displayed no significant change. As compared with the control, 25 days postflight the water-soluble protein concentration in the grey matter of the spinal cord increased significantly. There was a rise of the water-soluble proteins in the white matter of the spinal cord reaching the preflight level. Alkali-soluble proteins content in the spinal ganglia also increased significantly.

摘要

研究了用蒸馏水、0.85%氯化钠溶液和0.1N氢氧化钠依次从脊髓(腰膨大及脊髓神经节水平)中提取的各个蛋白质组分的含量。飞行后12小时,脊髓白质和灰质中水溶性蛋白质的含量显著降低。每1mg新鲜组织中脊髓和脊髓神经节结构中盐溶性和碱溶性蛋白质的含量无显著变化。与对照组相比,飞行后25天,脊髓灰质中水溶性蛋白质浓度显著增加。脊髓白质中水溶性蛋白质增加,达到飞行前水平。脊髓神经节中碱溶性蛋白质含量也显著增加。

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