Grabow L, Kremer G, Stannigel H, Wesierski P
Anasth Intensivther Notfallmed. 1982 Apr;17(2):96-7.
The intraoperative epidural opiate application seems to solve the problem of postoperative pain treatment after surgery of the vertebral column. For this purpose 2 mg of morphine in 1,0 ml NaCl-solution are placed epidurally in the root region, just prior to wound closure. 35 patients were treated in this manner and all of them, that means 100%, needed no analgetic in the first 16--24 hours after the operation. The patients feel remarkably better and nursing is facilitated. Intensive supervision however is essential during this time to prevent the risk of ascending diffusion of the morphine to the medullary regulating centers.
术中硬膜外应用阿片类药物似乎解决了脊柱手术后的术后疼痛治疗问题。为此，在伤口缝合前，将2毫克吗啡溶于1.0毫升氯化钠溶液中硬膜外注射到神经根区域。35例患者接受了这种治疗，所有患者，即100%，在术后16至24小时内不需要使用镇痛药。患者感觉明显好转，护理也更加便利。然而，在此期间必须进行密切监测，以防止吗啡向上扩散至髓质调节中枢的风险。
