Lysak V V, Fomichev Iu K
Antibiotiki. 1982 Mar;27(3):165-70.
The effect of UV light and mitomycin C as inductors of bacteriocins biosynthesis by Erwinia was studied. 46 strains of Erwinia were tested and the synthesis of bacteriocins was induced by irradiation with UV light only in 14 of them. The irradiation dose providing the highest increase of the bacteriocin titer was different for every strain. The survival of the strains ranged within 0.06 to 11.3 per cent. The time course of the bacteriocin synthesis induced by UV light in 9 strains of Erwinia was studied and it was shown that the process had common similar characteristics: gradual increasing of the bacteriocin titer immediately after exposure to UV light, reaching the maximum level 5-7 hours after incubation and its persisting for the subsequent observation period. Mitomycin indices bacteriocin production by the Erwinia strains tested only in individual cases, the character of the effect being dependent on the drug concentration and exposure time.
研究了紫外线和丝裂霉素C作为欧文氏菌产生细菌素生物合成诱导剂的作用。测试了46株欧文氏菌，仅在其中14株中通过紫外线照射诱导了细菌素的合成。使细菌素效价增加最高的照射剂量因菌株而异。菌株的存活率在0.06%至11.3%之间。研究了紫外线诱导9株欧文氏菌合成细菌素的时间进程，结果表明该过程具有共同的相似特征：暴露于紫外线后细菌素效价立即逐渐增加，培养5-7小时后达到最高水平，并在随后的观察期内持续存在。丝裂霉素仅在个别情况下诱导受试欧文氏菌菌株产生细菌素，其作用特征取决于药物浓度和暴露时间。
