Chengappa M M, Carter G R
Am J Vet Res. 1977 Aug;38(8):1183-5.
Of 33 strains of Pasteurella multocida examined, 14 showed bacteriocin activity and 17 were susceptible to bacteriocin. The activity was increased by about twofold if the cultures were induced with ultraviolet radiation; however, no increase in bacteriocin activity was observed if the potential producer strains were induced with mitomycin C. The bacteriocin activity of potential producer strains was increased if CaCl2 was incorporated in the medium. The patterns of bacteriocin susceptibility indicate that these substances may ultimately contribute to a typing scheme for the species. An extra-chromosomal genetic element was not detected when a potential producer strain was not detected when a potential producer strain was tested by the dye-buoyant density gradient method. This fact suggests that the genetic material responsible for bacteriocin activity in P multocida is located on the host chromosome proper.
在所检测的33株多杀性巴氏杆菌中，14株表现出细菌素活性，17株对细菌素敏感。如果用紫外线照射诱导培养物，活性会增加约两倍；然而，如果用丝裂霉素C诱导潜在的产生菌菌株，则未观察到细菌素活性增加。如果在培养基中加入氯化钙，潜在产生菌菌株的细菌素活性会增加。细菌素敏感性模式表明，这些物质最终可能有助于该物种的分型方案。当用染料浮力密度梯度法检测潜在产生菌菌株时，未检测到染色体外遗传元件。这一事实表明，多杀性巴氏杆菌中负责细菌素活性的遗传物质位于宿主染色体本身。
