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慢性创伤性胸主动脉瘤。手术治疗对自然病程的影响:对1950年至1980年报告病例的分析。

Chronic traumatic thoracic aneurysm. Influence of operative treatment on natural history: an analysis of reported cases, 1950-1980.

作者信息

Finkelmeier B A, Mentzer R M, Kaiser D L, Tegtmeyer C J, Nolan S P

出版信息

J Thorac Cardiovasc Surg. 1982 Aug;84(2):257-66.

PMID:7098511
Abstract

A total of 401 cases of chronic traumatic aneurysm reported during the past 30 years plus 12 cases from the University of Virginia Medical Center were analyzed. Forty-two percent of the patients developed signs or symptoms of aneurysm expansion within 5 years of injury: 85% within 20 years. Pain was the most frequently occurring sign or symptom, followed by serial enlargement on chest roentgenogram. Of the 60 patients who were followed without operative intervention, 20 died of their aortic lesions. For these patients, the combined risk of dying or developing signs or symptoms was 41% at 5 years. Over 300 patients underwent operative repair of the aneurysm. Operative mortality was 4.6%. Bleeding was the major cause of death as well as the most common major complication. When the survival probability of patients treated operatively was compared with that of patients treated nonoperatively, the operative group demonstrated a significantly higher survival probability.

摘要

对过去30年报告的401例慢性创伤性动脉瘤病例以及弗吉尼亚大学医学中心的12例病例进行了分析。42%的患者在受伤后5年内出现动脉瘤扩张的体征或症状:20年内为85%。疼痛是最常见的体征或症状,其次是胸部X线片上的连续增大。在60例未经手术干预而接受随访的患者中,20例死于主动脉病变。对于这些患者,5年时死亡或出现体征或症状的综合风险为41%。300多名患者接受了动脉瘤的手术修复。手术死亡率为4.6%。出血是主要死因,也是最常见的主要并发症。将接受手术治疗的患者的生存概率与未接受手术治疗的患者的生存概率进行比较时,手术组的生存概率显著更高。

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