3,3',5'-三碘甲状腺原氨酸（反式T3）的尿排泄量

Urinary excretion of 3,3',5'-triiodothyronine (reverse T3).

作者信息

Faber J, Kirkegaard B C, Rogowski P, Siersbaek-Nielsen K, Friis T

出版信息

Clin Endocrinol (Oxf). 1978 Sep;9(3):279-82. doi: 10.1111/j.1365-2265.1978.tb02211.x.

DOI:10.1111/j.1365-2265.1978.tb02211.x

Abstract

A simple and sensitive radioimmunoassay for reverse T3 in urine using small Sephadex G25 fine columns is described. The recovery of rT3 added to urine was on average 101.0 +/- 4.2% (mean +/- SEM). Detection limit was 4 pg/column. Urine excretion of rT3 (mean +/- SD) was 72.0 +/- 32.1 ng/24 h in 61 healthy euthyroid subjects with a slight increase with age (P less than 0.05), 28.8 +/- 18.2 ng/24 h in 12 hypothyroid patients and 183.6 +/- 79.7 ng/24 in 25 hyperthyroid patients.

摘要

本文描述了一种使用小型葡聚糖凝胶G25细柱对尿中反三碘甲状腺原氨酸进行简单且灵敏的放射免疫分析方法。添加到尿液中的反三碘甲状腺原氨酸的回收率平均为101.0±4.2%（平均值±标准误）。检测限为4 pg/柱。61例健康甲状腺功能正常的受试者尿中反三碘甲状腺原氨酸的排泄量（平均值±标准差）为72.0±32.1 ng/24小时，且随年龄略有增加（P<0.05）；12例甲状腺功能减退患者为28.8±18.2 ng/24小时；25例甲状腺功能亢进患者为183.6±79.7 ng/24小时。