Weide L G, Clark M A, Rupert C S, Shay J W
Somatic Cell Genet. 1982 Jan;8(1):15-21. doi: 10.1007/BF01538647.
A genetic technique has been developed for isolating nuclear hybrids which are products of fusion between karyoplasts and whole cells. Nuclear hybrids have greatly reduced mitochondrial component obtained from the nuclear donor and exhibit differences when compared to the corresponding whole-cell hybrids, such as better long-term survival and accelerated chromosome segregation. These results suggest that divergent mitochondria in a cell-fusion product may have adverse effects on survival.
已开发出一种遗传技术，用于分离核杂种，核杂种是核质体与全细胞融合的产物。核杂种的线粒体成分大量减少，这些成分来自核供体，与相应的全细胞杂种相比表现出差异，例如具有更好的长期存活率和加速的染色体分离。这些结果表明，细胞融合产物中不同的线粒体可能对存活产生不利影响。
