阿司匹林对中枢神经系统的影响。
Central nervous system effects of aspirin.
作者信息
Fink M, Irwin P
出版信息
Clin Pharmacol Ther. 1982 Sep;32(3):362-5. doi: 10.1038/clpt.1982.172.
PMID:7105626
Abstract
The EEG effects of aspirin at single doses of 0.65 and 1.95 gm were studied in normal adult men. Compared to placebo, 1.95 gm affected the quantitative EEG, symptom self reports, and cognitive functions. The effects of 0.65 gm. were similar in direction and pattern, but failed measurable significance. The EEG profile of aspirin is distinct from that of other psychoactive substances. Its interaction with sedative substances should be considered in routine clinical use.
摘要
研究了单剂量0.65克和1.95克阿司匹林对正常成年男性脑电图的影响。与安慰剂相比，1.95克剂量的阿司匹林影响了脑电图定量分析、症状自我报告和认知功能。0.65克剂量的影响在方向和模式上相似，但未达到可测量的显著性。阿司匹林的脑电图特征与其他精神活性物质不同。在常规临床应用中应考虑其与镇静物质的相互作用。
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