Gebhardt C, Stolte M
Chirurg. 1982 May;53(5):325-7.
A total atrophy of the exocrine pancreas by duct occlusion can only be achieved if the whole duct system is filled. Nevertheless, a residual secretion--poor in enzymes--from the tubular glands of the pancreatic duct is possible. Long-term results of pancreatic duct occlusion are now available not only from animal experiments, but also after application in humans, --the results are comparable. The effectiveness in the treatment of chronic pancreatitis can be demonstrated: in a total of 141 partial duodenopancreatectomies with intraoperative "burning out" of the pancreatic tail, we did'nt observe any postoperative complications from the remaining pancreatic tail and over the course of up to a maximum of 4 years we saw only a single case of recurrent pancreatitis. After partial duodenopancreatectomy for pancreatic cancer insufficiency of the pancreaticojejunostomy occurs in about 14%. Therefore, also in cancer surgery the application of duct occlusion to prevent postoperative complications should be discussed.
只有当整个导管系统都被填满时，通过导管阻塞才能实现外分泌胰腺的完全萎缩。然而，胰腺导管的管状腺仍可能分泌少量酶的残余分泌物。现在，不仅在动物实验中可以获得胰腺导管阻塞的长期结果，而且在应用于人类后也可以获得——结果是可比的。可以证明其在治疗慢性胰腺炎方面的有效性：在总共141例术中对胰尾进行“烧灼”的部分十二指肠胰腺切除术中，我们没有观察到剩余胰尾出现任何术后并发症，并且在长达4年的时间里，我们仅看到1例复发性胰腺炎病例。在因胰腺癌进行部分十二指肠胰腺切除术后，胰空肠吻合口功能不全的发生率约为14%。因此，在癌症手术中，也应讨论应用导管阻塞以预防术后并发症的问题。
