Gut. 1982 Sep;23(9):774-6. doi: 10.1136/gut.23.9.774.
This report presents the diagnostic value of brush cytology in gastric cancer. Gastric biopsies and brush cytology were performed in 155 patients with gastric cancer and 48 with benign gastric disease. The positive rate for biopsy and brush cytology in cancer patients (including 11 cases of early gastric cancer) was 74.2% and 76.8% respectively. The positive rate of biopsy with concomitant brush cytology was 87.7, which was superior to that of biopsy or brush cytology alone (p less than 0.01). In 29 cases of gastric cancer involving the cardiac region. 20 were biopsy positive (69%) and 22 were brush cytology positive (75.9%). Biopsy with brush cytology was positive in 27 cases (93.1%) and gave better results than biopsy alone (p less than 0.01). The positive rate of biopsy with concomitant brush cytology in Borrmann type I, II, and III lesions (89.7%) was significantly higher than in Borrmann type IV lesions (50%). In the 48 patients with benign gastric lesion, biopsy and brush cytology each provided two false positives. The study shows that the combination of biopsy and brush cytology increases diagnostic accuracy for gastric cancer.
本报告介绍了刷检细胞学在胃癌中的诊断价值。对155例胃癌患者和48例良性胃部疾病患者进行了胃活检和刷检细胞学检查。癌症患者（包括11例早期胃癌）的活检和刷检细胞学阳性率分别为74.2%和76.8%。活检联合刷检细胞学的阳性率为87.7%，优于单独的活检或刷检细胞学（p<0.01）。在29例累及贲门区的胃癌病例中，20例活检阳性（69%），22例刷检细胞学阳性（75.9%）。活检联合刷检细胞学检查27例阳性（93.1%），结果优于单独活检（p<0.01）。Borrmann I型、II型和III型病变中活检联合刷检细胞学的阳性率（89.7%）显著高于Borrmann IV型病变（50%）。在48例良性胃部病变患者中，活检和刷检细胞学各出现2例假阳性。研究表明，活检与刷检细胞学相结合可提高胃癌的诊断准确性。
