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白来航鸡中五个特定内源性逆转录病毒基因座的染色体聚类

Chromosomal clustering of five defined endogenous retrovirus loci in White Leghorn chickens.

作者信息

Tereba A, Astrin S M

出版信息

J Virol. 1982 Aug;43(2):737-40. doi: 10.1128/JVI.43.2.737-740.1982.

DOI:10.1128/JVI.43.2.737-740.1982
PMID:7109040
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC256177/
Abstract

By using in situ hybridization, we localized three endogenous chicken retrovirus loci associated with the gs- chf- phenotype to distinct regions on chromosome 1. These three loci, ev4, ev5, and ev8, along with the two other known gs- chf--associated loci in White Leghorn chickens, ev1 and ev13, appear to be evenly distributed along chromosome 1, occurring approximately every 1.8 X 10(7) base pairs. The presence of all five loci on chromosome 1 represents a highly nonrandom distribution and all but eliminates a mechanism of independent random integration events for the generation of these loci.

摘要

通过原位杂交技术,我们将与gs-chf-表型相关的三个内源性鸡逆转录病毒基因座定位到了1号染色体上的不同区域。这三个基因座,即ev4、ev5和ev8,连同白来航鸡中另外两个已知的与gs-chf-相关的基因座ev1和ev13,似乎沿着1号染色体均匀分布,大约每1.8×10⁷个碱基对出现一个。1号染色体上所有五个基因座的存在代表了一种高度非随机的分布,几乎排除了这些基因座产生的独立随机整合事件机制。

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Chromosomal localization of three endogenous retrovirus loci associated with virus production in White Leghorn chickens.与白来航鸡病毒产生相关的三个内源性逆转录病毒基因座的染色体定位。
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引用本文的文献

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本文引用的文献

1
Chromosomal localization of ev-1, a frequently occurring endogenous retrovirus locus in white Leghorn chickens, by in situ hybridization.通过原位杂交对ev-1(白来航鸡中常见的内源性逆转录病毒位点)进行染色体定位。
J Virol. 1980 Sep;35(3):888-94. doi: 10.1128/JVI.35.3.888-894.1980.
2
5'-terminal deletions are a common feature of endogenous retrovirus loci located on chromosome 1 of White Leghorn chickens.5' 端缺失是白来航鸡 1 号染色体上内源性逆转录病毒基因座的一个常见特征。
J Virol. 1981 Dec;40(3):920-6. doi: 10.1128/JVI.40.3.920-926.1981.
3
Cell oncogenes are located on the large microchromosomes in chicken cells.
Virology. 1982 Jan 30;116(2):654-7. doi: 10.1016/0042-6822(82)90159-3.
4
Alterations in the genomes of avian sarcoma viruses.禽肉瘤病毒基因组的改变。
Virology. 1982 Mar;117(2):456-74. doi: 10.1016/0042-6822(82)90484-6.
5
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J Virol. 1981 Jul;39(1):282-9. doi: 10.1128/JVI.39.1.282-289.1981.
6
Integration of avian sarcoma virus DNA in chicken cells.
Virology. 1981 Jan 15;108(1):208-21. doi: 10.1016/0042-6822(81)90539-0.
7
Transcriptional products and DNA structure of endogenous avian proviruses.内源性禽逆转录病毒的转录产物与DNA结构
Cold Spring Harb Symp Quant Biol. 1980;44 Pt 2,:1111-21. doi: 10.1101/sqb.1980.044.01.120.
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Ten genetic loci in the chicken that contain structural genes for endogenous avian leukosis viruses.鸡体内十个含有内源性禽白血病病毒结构基因的基因座。
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Phys Med Biol. 1970 Jul;15(3):447-56. doi: 10.1088/0031-9155/15/3/005.