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肺癌的内镜下管理与血卟啉衍生物光疗

Endoscopic management of lung cancer with hematoporphyrin derivative phototherapy.

作者信息

Cortese D A, Kinsey J H

出版信息

Mayo Clin Proc. 1982 Sep;57(9):543-7.

PMID:7109682
Abstract

This paper demonstrates the potential use of hematoporphyrin derivative in the phototherapy of bronchogenic cancer. We report on 10 patients (a total of 11 carcinomas) with cancer involving the tracheobronchial tree who completed one course of this new treatment administered via the flexible fiberoptic bronchoscope. Four superficial carcinomas showed a complete response; five larger carcinomas showed a partial response, Two patients, each with a large cancer extending beyond the bronchial wall, died within 11 days after treatment.

摘要

本文证明了血卟啉衍生物在支气管源性癌光疗中的潜在用途。我们报告了10例(共11个癌灶)累及气管支气管树的癌症患者,他们完成了通过可弯曲纤维支气管镜进行的这一新治疗的一个疗程。4例浅表癌灶显示完全缓解;5例较大癌灶显示部分缓解。2例患有超出支气管壁的大型癌灶的患者在治疗后11天内死亡。

相似文献

1
Endoscopic management of lung cancer with hematoporphyrin derivative phototherapy.肺癌的内镜下管理与血卟啉衍生物光疗
Mayo Clin Proc. 1982 Sep;57(9):543-7.
2
Hematoporphyrin-derivative phototherapy for local treatment of cancer of the tracheobronchial tree.血卟啉衍生物光疗法用于气管支气管树癌的局部治疗。
Ann Otol Rhinol Laryngol. 1982 Nov-Dec;91(6 Pt 1):652-5. doi: 10.1177/000348948209100628.
3
Hematoporphyrin derivative phototherapy in the treatment of bronchogenic carcinoma.血卟啉衍生物光疗在支气管癌治疗中的应用
Chest. 1984 Jul;86(1):8-13. doi: 10.1378/chest.86.1.8.
4
Bronchoscopic phototherapy using hematoporphyrin derivative.使用血卟啉衍生物的支气管镜光疗。
Surg Clin North Am. 1984 Oct;64(5):941-6. doi: 10.1016/s0039-6109(16)43437-7.
5
[Fiberoptic bronchoscopy-gold vapor laser treatment of bronchogenic carcinoma].[纤维支气管镜-金蒸汽激光治疗支气管癌]
Zhonghua Jie He He Hu Xi Za Zhi. 1988 Feb;11(1):25-6, 63.
6
Bronchoscopic phototherapy with hematoporphyrin derivative for treatment of localized bronchogenic carcinoma: a 5-year experience.应用血卟啉衍生物的支气管镜光疗治疗局限性支气管源性癌:5年经验
Mayo Clin Proc. 1987 Jan;62(1):8-14. doi: 10.1016/s0025-6196(12)61520-1.
7
Photoradiation therapy of endobronchial lung cancer. Large obstructing tumors, nonobstructing tumors, and early-stage bronchial cancer lesions.支气管内肺癌的光辐射治疗。巨大阻塞性肿瘤、非阻塞性肿瘤及早期支气管癌病变。
Clin Chest Med. 1985 Jun;6(2):255-75.
8
HpD photodynamic therapy for obstructing lung cancer.血卟啉衍生物光动力疗法治疗阻塞性肺癌
Prog Clin Biol Res. 1984;170:727-45.
9
Clinical application of a new endoscopic technique for detection of in situ bronchial carcinoma.一种用于检测原位支气管癌的新型内镜技术的临床应用
Mayo Clin Proc. 1979 Oct;54(10):635-41.
10
Bronchoscopic localization and treatment of occult lung cancer.隐匿性肺癌的支气管镜定位与治疗
Chest. 1989 Oct;96(4):919-21. doi: 10.1378/chest.96.4.919.

引用本文的文献

1
Bronchoscopic palliation of primary lung cancer: single or multimodality therapy?原发性肺癌的支气管镜姑息治疗:单一治疗还是多模式治疗?
Surg Endosc. 2004 Jun;18(6):931-6. doi: 10.1007/s00464-003-9202-x. Epub 2004 Apr 27.
2
Current concepts in gastrointestinal photodynamic therapy.胃肠道光动力治疗的当前概念
Ann Surg. 1999 Jul;230(1):12-23. doi: 10.1097/00000658-199907000-00003.
3
Experimental studies to assess the potential of photodynamic therapy for the treatment of bronchial carcinomas.评估光动力疗法治疗支气管癌潜力的实验研究。
Thorax. 1993 May;48(5):474-80. doi: 10.1136/thx.48.5.474.
4
Phototherapy in tumors.肿瘤中的光疗。
World J Surg. 1983 Nov;7(6):700-9. doi: 10.1007/BF01655209.
5
Laser therapy in 100 tracheobronchial tumours.100例气管支气管肿瘤的激光治疗
Thorax. 1985 May;40(5):341-5. doi: 10.1136/thx.40.5.341.
6
Photodynamic therapy for colorectal disease.用于结直肠疾病的光动力疗法。
Int J Colorectal Dis. 1989;4(1):15-9. doi: 10.1007/BF01648544.
7
Endoscopic photodynamic therapy with hematoporphyrin derivative for primary treatment of gastrointestinal neoplasms in inoperable patients.采用血卟啉衍生物的内镜光动力疗法用于无法手术患者胃肠道肿瘤的初始治疗
Dig Dis Sci. 1990 May;35(5):545-52. doi: 10.1007/BF01540400.
8
Local eradication of rat colon cancer with photodynamic therapy: correlation of distribution of photosensitiser with biological effects in normal and tumour tissue.光动力疗法对大鼠结肠癌的局部根除:光敏剂在正常组织和肿瘤组织中的分布与生物学效应的相关性
Gut. 1991 May;32(5):517-23. doi: 10.1136/gut.32.5.517.
9
Endoscopic palliation of tracheobronchial malignancies.气管支气管恶性肿瘤的内镜下姑息治疗。
Thorax. 1991 May;46(5):325-33. doi: 10.1136/thx.46.5.325.