Inada S, Kajii K, Takenaga M, Fujita M, Kawamura K, Yanaihara N
Radioisotopes. 1982 Apr;31(4):190-4. doi: 10.3769/radioisotopes.31.4_190.
A radioimmunoassay for dihydroergotoxine was developed using antiserum frm the rabbit injected with a dihydromethylergometrine-bovine serum albumin conjugate. The antiserum was found to be highly specific to dihydroergot alkaloids. The minimum detectable amount of dihydroergotoxine methanesulfonate with this assay system was about 100 pg/ml in serum. Practical applicability of the assay system was proved by measuring dog serum concentrations after oral administration of dihydroergotoxine methanesulfonate.
使用注射了二氢甲基麦角新碱-牛血清白蛋白结合物的兔抗血清，开发了一种用于二氢麦角毒碱的放射免疫分析方法。发现该抗血清对二氢麦角生物碱具有高度特异性。该分析系统检测甲磺酸二氢麦角毒碱的最低可检测量在血清中约为100 pg/ml。通过测量口服甲磺酸二氢麦角毒碱后犬血清浓度，证明了该分析系统的实际适用性。
