Earp J A, Ory M G, Strogatz D S
Am J Public Health. 1982 Oct;72(10):1146-54. doi: 10.2105/ajph.72.10.1146.
The effectiveness of two social support strategies designed to lower hypertensive patients' blood pressure were compared to each other and to a control group (N = 63) receiving routine care in a randomized clinical trial extending over a period of two years. Group 1 (N = 99) received visits and had family members actively participate in their care through home blood pressure monitoring; Group 2 (N = 56) received home visits from nurses and pharmacists. All groups were predominantly Black. After the first year of the trial, the proportion of patients with uncontrolled diastolic blood pressure (greater than or equal to 95mm Hg) had declined significantly for all three groups; no group showed a statistically significant advantage. However, during the last six months of the second year (after visiting had ended), both Groups 1 and 2 demonstrated clear superiority in DBP control over Group 3, achieving borderline statistical significance (p = .07) when multivariable analysis was performed to control for potential confounders. Supplementing routine care with periodic home visits produced an additional 21 per cent of patients with well-controlled DBP, while involving family members plus visits produced a 17 per cent improvement in the percentage of patients with DBP less than 95mm Hg. However, neither support strategy was clearly more effective than the other over time. The efficacy of the interventions is discussed with respect to cost and feasibility of implementation.
在一项为期两年的随机临床试验中,比较了旨在降低高血压患者血压的两种社会支持策略的效果,并与接受常规护理的对照组(N = 63)进行了对比。第1组(N = 99)接受家访,家庭成员通过家庭血压监测积极参与其护理;第2组(N = 56)接受护士和药剂师的家访。所有组主要为黑人。试验的第一年过后,三组中舒张压未得到控制(大于或等于95毫米汞柱)的患者比例均显著下降;没有一组显示出统计学上的显著优势。然而,在第二年的最后六个月(家访结束后),第1组和第2组在舒张压控制方面均明显优于第3组,在进行多变量分析以控制潜在混杂因素时,达到了临界统计学显著性(p = 0.07)。定期家访补充常规护理使舒张压得到良好控制的患者额外增加了21%,而让家庭成员参与并进行家访使舒张压低于95毫米汞柱的患者比例提高了17%。然而,随着时间的推移,两种支持策略都没有明显比另一种更有效。文中讨论了干预措施在成本和实施可行性方面的效果。