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Acute toxicity of prostaglandin Bx in male, albino, ICR mice.

作者信息

Burkman A M

出版信息

Res Commun Chem Pathol Pharmacol. 1982 Jul;37(1):97-104.

PMID:7123004
Abstract

Median lethal doses were estimated for PGBx administered to mice by the intraperitoneal and intravenous routes. The incidence of lethality (and therefore the LD50) was time dependent over a 96 hour period. The animals were active, were responsive and took nourishment during the 4-day post-injection period so that they apparently died from the direct effects of PGBx (or its metabolites) and not as a consequence of depression-induced dehydration or starvation.

摘要

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