McClelland C J, Craig B F, Crockard H A
J Neurol Neurosurg Psychiatry. 1978 Nov;41(11):1043-7. doi: 10.1136/jnnp.41.11.1043.
One hundred and seventy-two cases of intracranial abscesses, obtained from Neurosurgical and Centralised Autopsy Records for Northern Ireland for the 30 years, 1947--1976, have been reviewed. The incidence of the disease has fallen from five to three per million of population per year over the past three decades. Intracranial abscesses were three times as common in males as in females. Twenty-nine per cent of the abscesses were in the temporal lobe, 25% frontal, 10% parietal, 6% cerebellar, 3% occipital, and 7% were either subdural or in deep sites such as the thalamus; the remainder (20%) were multiple. Multiple and occipital abscesses were all fatal, temporal and parietal abscesses were associated with a 65% mortality, and 45% of patients with frontal abscesses died. Chronic suppurative otitis media was the single largest cause, and it was the only aetiological factor to have shown a progressive decline over 30 years. For those seen and treated in the neurosurgical unit the mortality was 53%, but if those obtained from the necropsy records were included the overall mortality was 70%.
回顾了1947年至1976年这30年间从北爱尔兰神经外科和集中尸检记录中获取的172例颅内脓肿病例。在过去三十年中，该疾病的发病率已从每年每百万人口5例降至3例。颅内脓肿在男性中的发生率是女性的三倍。29%的脓肿位于颞叶，25%位于额叶，10%位于顶叶，6%位于小脑，3%位于枕叶，7%为硬膜下或位于丘脑等深部部位；其余（20%）为多发性。多发性和枕叶脓肿均为致命性，颞叶和顶叶脓肿的死亡率为65%，额叶脓肿患者的死亡率为45%。慢性化脓性中耳炎是单一最大病因，也是30年来唯一呈逐渐下降趋势的病因。在神经外科病房接受诊治的患者死亡率为53%，但如果将尸检记录中的病例包括在内，总体死亡率为70%。
