Doyle P J, Ward-McQuaid J N, Smith A M
Br J Surg. 1982 Oct;69(10):617-9. doi: 10.1002/bjs.1800691020.
A total of 4000 consecutive cholecystectomies performed over a period of 25 years has been analysed to determine whether routine peroperative cholangiography (PC) has influenced overall mortality. The patients have been divided into four cohorts of 1000, the first cohort before the introduction of PC, two covering the period of introduction of PC and the final cohort when PC was an established routine. A significant fall in overall mortality has been demonstrated, but when the patients are divided into simple cholecystectomy and the group undergoing additional choledochotomy there is no significant fall in the mortality rate. The mortality rate for the latter group is three or four times greater than that for the cholecystectomy alone group. The main contribution to the lower mortality is the reduced duct exploration rate following the introduction of PC. The stone recovery rate has improved from 34 to 71 per cent. The use of routine PC during cholecystectomy is recommended.
对25年间连续进行的4000例胆囊切除术进行了分析,以确定术中常规胆管造影(PC)是否影响总体死亡率。患者被分为四个队列,每个队列1000例,第一个队列在PC引入之前,两个队列涵盖PC引入期间,最后一个队列是PC成为既定常规操作时。总体死亡率有显著下降,但当患者分为单纯胆囊切除术组和接受附加胆总管切开术组时,死亡率没有显著下降。后一组的死亡率比单纯胆囊切除术组高三到四倍。死亡率降低的主要原因是PC引入后胆管探查率降低。结石取出率从34%提高到了71%。建议在胆囊切除术中使用常规PC。