Kopf A W, Rodríguez-Sains R S, Rigel D S, Friedman R J, Bart R S, Grier W R, Mintzis M M, Postel A H
J Dermatol Surg Oncol. 1982 Sep;8(9):765-70. doi: 10.1111/j.1524-4725.1982.tb02679.x.
In a consecutive series of 648 superficial spreading melanomas a significantly better 5-year disease-free survival rate was observed for patients whose primary tumors were 14 mm or less in diameter when compared with those 15 mm or larger in diameter. Other distinguishing features of the group of "smaller" superficial spreading melanomas were that they occurred in younger patients; were of shorter durations; were more common in women; occurred disproportionately on the lower limbs; were less elevated; tended to be round in shape; were thinner (Breslow); penetrated less deeply (Clark levels); showed less histologic regression; and developed fewer metastases. Based on these findings it is recommended that educational programs be undertaken for the medical profession and for the public to promote early diagnosis and prompt treatment of superficial spreading melanomas when they are small in diameter and more often curable. A color atlas of "small" melanomas is presented.
