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多重禽流感感染:异源禽类宿主对非嗜性病毒的选择。

Multiple avian influenza infection: selection of a non-avid virus by a heterologous avian host.

作者信息

King A P, Shortridge K F

出版信息

Res Vet Sci. 1982 Jul;33(1):127-9.

PMID:7134641
Abstract

Experimental infection of domestic fowl, ducks and geese with an influenza A virus (H7N2) isolated from a domestic duck showed that this virus was apathogenic for these poultry. A second virus (H6N2), also apathogenic and more 'non-avid' than any such isolates previously recognised in surveillance of domestic poultry in Hong Kong, was isolated from one goose after H7N2 shedding had ceased. This goose, in effect, acted as a selective isolation system for the H6N2 virus whose presence in the field isolate could not be detected in spite of multiple passage in embryonated eggs.

摘要

用从一只家鸭分离出的甲型流感病毒(H7N2)对家禽、鸭和鹅进行实验性感染,结果表明该病毒对这些禽类无致病性。在H7N2排毒停止后,从一只鹅体内分离出第二种病毒(H6N2),该病毒同样无致病性,且比之前在香港家禽监测中发现的任何此类分离株“亲和力更低”。实际上,这只鹅起到了对H6N2病毒的选择性分离系统的作用,尽管在鸡胚中多次传代,仍无法在野外分离株中检测到该病毒的存在。

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