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从香港家禽中分离出的甲型流感病毒亚型的多样性。

Diversity of influenza A virus subtypes isolated from domestic poultry in Hong Kong.

作者信息

Shortridge K F, Butterfield W K, Webster R G, Campbell C H

出版信息

Bull World Health Organ. 1979;57(3):465-9.

Abstract

The second phase of a 2-year influenza virus surveillance programme of domestic avian species in Hong Kong (up to October 1977) yielded influenza A virus, Newcastle disease virus, and Hong Kong paramyxovirus, as well as unidentified haemagglutinating agents. These viruses were isolated from the trachea or cloaca of apparently healthy domestic ducks, geese, and chickens originating from China and Hong Kong. Twenty-five combinations of haemagglutinin and neuraminidase surface antigens were identified from the 136 influenza A viruses isolated. Eight of the combinations do not appear to have been previously reported - Hav3Nav2, Hav4Nav2, Hav4Nav4, Hav4Nav5, Hav4Neq1, Hav6Nav4, Hav6Nav6, and Hav9Nav1. The existence of such a diverse pool of influenza virus genetic information may play a role in the emergence of new human pandemic strains.

摘要

香港一项为期两年的本地禽类流感病毒监测计划(截至1977年10月)的第二阶段,分离出了甲型流感病毒、新城疫病毒、香港副粘病毒以及未鉴定的血凝剂。这些病毒是从来自中国内地和香港的表面健康的家鸭、家鹅和家鸡的气管或泄殖腔中分离出来的。从分离出的136株甲型流感病毒中鉴定出了25种血凝素和神经氨酸酶表面抗原组合。其中8种组合似乎此前未曾报道过——Hav3Nav2、Hav4Nav2、Hav4Nav4、Hav4Nav5、Hav4Neq1、Hav6Nav4、Hav6Nav6和Hav9Nav1。如此多样的流感病毒基因信息库的存在可能在新型人类大流行毒株的出现中发挥作用。

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