Klingberg F, Klingberg H
Acta Biol Med Ger. 1982;41(5):497-500.
Bilateral symmetric lesions of the posterior thalamic nucleus reduced the preoperatively learnt avoidance responses in Long-Evans hooded rats strongly. Postoperative acquisition of conditioned avoidance reflexes was rather low in each rat in a simple runway and impossible in an alternation task. Thresholds of reactions to pain (withdrawal of paws from the grid floor) were significantly increased. The lesioned rats had trouble to find the way out, as if they had difficulties to localize the source of punishment or to associate pain information with any other cues.
丘脑后核的双侧对称性损伤显著降低了长-伊文斯蒙面大鼠术前习得的回避反应。在简单跑道上，每只大鼠术后条件性回避反射的习得率相当低，而在交替任务中则无法习得。对疼痛的反应阈值（爪子从网格地板上缩回）显著提高。损伤的大鼠难以找到出路，就好像它们难以定位惩罚源或将疼痛信息与任何其他线索联系起来。
