Klingberg F, Klingberg H
Acta Biol Med Ger. 1978;37(11-12):1783-5.
Hooded rats of the Long-Evans strain with isolated bilateral lesions of the nucleus mediodorsalis thalami (MD) were not able to avoid foot-shocks in a simple runway and in the jumping test. They even did not move and showed no emotional reactions during the conditioned stimulus. The lesions did not change spontaneous behaviour, motor patterns or the thresholds of pain reactivity. The animals displayed less spontaneous and goal-directed orienting responses. The possible participation of MD in a functional system realizing certain kinds of prognosis is discussed.
对长-伊文斯品系的有双侧丘脑背内侧核(MD)孤立性损伤的带帽大鼠进行研究,发现它们在简单跑道和跳跃试验中无法避免足部电击。在条件刺激期间,它们甚至不移动,也没有表现出情绪反应。这些损伤并未改变自发行为、运动模式或疼痛反应阈值。这些动物表现出较少的自发和目标导向性定向反应。文中讨论了MD在实现某些类型预后的功能系统中的可能参与情况。