Barkin J S, Pereiras R, Hill M, Levi J, Isikoff M, Rogers A I
Dig Dis Sci. 1982 Nov;27(11):1011-4. doi: 10.1007/BF01391747.
The pre-operative diagnosis of a pancreatic abscess was not considered in a comprehensive review in 1972. However, advances in technology (Ultrasound--US, Computed Tomography--CT) has allowed guided percutaneous needle aspiration (PNA) of suspected pancreatic lesions. The purpose of this study was to evaluate the safety and diagnostic ability of PNA to differentiate acute pancreatic inflammatory masses from pancreatic abscess (PA). Thirteen patients underwent PNA after US or CT revealed an acute pancreatic inflammatory mass (12/13 cystic). One patient underwent a second aspiration. Clinical features T degrees--101.3 degrees F mean (13/13), leukocytosis 14,400 cu/mm (11/13). Aspirated material was gram-stained and examined for bacteria and leukocytes and cultured.
PNA was accomplished successfully in all patients. Aspirate revealed bacteria in nine and pancreatic abscess was confirmed at surgery (8) or post-mortem exam (1). Four of five patients in whom no bacteria were visualized had medical resolution, the fifth had continued T degree and underwent a second aspiration which diagnosed a PA. PA contained moderate to large number of PML via aspiration.
PNA provides a potentially important and safe diagnosis adjunct to earlier accurate differential diagnosis of pancreatic inflammatory masses from pancreatic abscess.
1972年的一项全面综述中未考虑胰腺脓肿的术前诊断。然而,技术的进步(超声——US、计算机断层扫描——CT)使得对疑似胰腺病变能够进行超声引导下经皮穿刺抽吸(PNA)。本研究的目的是评估PNA鉴别急性胰腺炎性肿块与胰腺脓肿(PA)的安全性和诊断能力。13例患者在超声或CT显示急性胰腺炎性肿块(13例中有12例为囊性)后接受了PNA。1例患者接受了二次抽吸。临床特征:体温——平均101.3华氏度(13/13),白细胞增多14,400/mm³(11/13)。对抽吸物进行革兰氏染色,检查细菌和白细胞并进行培养。
所有患者的PNA均成功完成。抽吸物在9例中发现细菌,手术(8例)或尸检(1例)证实为胰腺脓肿。5例未发现细菌的患者中有4例经内科治疗缓解,第5例体温持续升高,接受二次抽吸后诊断为PA。通过抽吸发现PA含有中度至大量的多形核白细胞。
PNA为早期准确鉴别胰腺炎性肿块与胰腺脓肿提供了一种潜在重要且安全的诊断辅助手段。