Bender K I, Panchenko E V
Farmakol Toksikol. 1982 Sep-Oct;45(5):38-42.
It has been demonstrated in experiments on rats that in the skeletal muscle, morphine and promedol cause, during disconnection of efferent innervation with pavulon, a dose-dependent reduction in oxygen tension (OT) and an increase in the oxygen consumption rate constant (OCRC). During disconnection of the central mechanisms of muscle tone control with sodium thiopental, morphine and, to a greater degree, promedol decreased OT. The OCRC was markedly decreased under the effect of morphine in a dose of 25 mg/kg.
在大鼠实验中已证明，在使用泮库溴铵切断传出神经支配期间，吗啡和异丙嗪在骨骼肌中会导致氧张力（OT）呈剂量依赖性降低以及氧消耗速率常数（OCRC）增加。在使用硫喷妥钠切断肌张力控制的中枢机制期间，吗啡以及在更大程度上异丙嗪会降低OT。在25毫克/千克剂量的吗啡作用下，OCRC明显降低。
