Comparison of methods for the determination of beta-aspartylglycine in fecal supernatants of leukemic patients treated with antimicrobial agents.

Beta-Aspartylglycine is an indicator of the absence of bacterial enzymatic activity in the intestinal tract. This study describes and compares four methods--(1) dansylation with thin-layer chromatography, (2) ion-exchange chromatography, (3) thin-layer electrophoresis, (4) high-voltage paper electrophoresis--to determine the concentration of beta-aspartylglycine in fecal supernatants of leukemic patients treated with antimicrobial agents.