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在由流产感染以及有效感染的猴细胞制备的无细胞裂解物中,人腺病毒mRNA的正常翻译。

Normal translation of human adenovirus mRNA in cell-free lysates prepared from abortively as well as productively infected monkey cells.

作者信息

Quinlan M P, Klessig D F

出版信息

J Virol. 1982 Oct;44(1):426-30. doi: 10.1128/JVI.44.1.426-430.1982.

Abstract

A variety of mRNAs, including adenovirus-specified mRNAs isolated from infected human cells, were translated with similar efficiencies in S10 cell-free lysates prepared from productively and abortively infected monkey cells. These results may suggest that reduced synthesis of the late viral proteins in abortively infected monkey cells is not due to a defect in the protein-synthesizing apparatus of the cell.

摘要

多种信使核糖核酸,包括从受感染的人类细胞中分离出的腺病毒特异性信使核糖核酸,在由高效感染和流产感染的猴细胞制备的S10无细胞裂解物中以相似的效率进行翻译。这些结果可能表明,在流产感染的猴细胞中晚期病毒蛋白合成减少并非由于细胞蛋白质合成装置存在缺陷。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ea6/256279/0de17b885b3a/jvirol00151-0437-a.jpg

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