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淋巴细胞性脑脊神经根炎(班沃思综合征)的临床及脑脊液检查结果

Clinical and cerebrospinal fluid findings in lymphocytic meningo-radiculitis (Bannwarth's syndrome).

作者信息

Hindfelt B, Jeppsson P G, Nilsson B, Olsson J E, Ryberg B, Sörnäs R

出版信息

Acta Neurol Scand. 1982 Oct;66(4):444-53. doi: 10.1111/j.1600-0404.1982.tb06866.x.

Abstract

11 patients with lymphocytic meningo-radiculitis (Bannwarth's syndrome) are described. The disease is characterized by intensive pain, often radiating and migrating, and neurological deficits, i.e. peripheral facial palsies, as well as disseminated radiculopathies. In 4 patients the onset was preceded by an arthropod bite, close to which 3 patients exhibited an erythema chronicum migrans. In the cerebrospinal fluid there was a mononuclear pleocytosis, predominantely by lymphocytes. In the early stages, a plasma cell reaction was frequently encountered. Protein analysis indicated a defect in the blood brain barrier and an intrathecal synthesis of IgG. All patients recovered almost completely from their neurological symptoms within 1-2 months, irrespective of treatment.

摘要

本文描述了11例淋巴细胞性脑膜神经根炎(班沃思综合征)患者。该疾病的特征为剧烈疼痛,常呈放射性且游走性,伴有神经功能缺损,即周围性面瘫以及播散性神经根病。4例患者发病前有节肢动物叮咬史,其中3例在叮咬部位出现慢性游走性红斑。脑脊液检查显示单核细胞增多,以淋巴细胞为主。在疾病早期,常可见浆细胞反应。蛋白质分析表明存在血脑屏障缺陷及鞘内IgG合成。所有患者无论是否接受治疗,均在1 - 2个月内神经症状几乎完全恢复。

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