Murray N, Kristoferitsch W, Stanek G, Steck A J
J Neurol. 1986 Aug;233(4):224-7. doi: 10.1007/BF00314024.
The specificity of immunoglobulin (Ig) for components of Borrelia burgdorferi was investigated in cerebrospinal fluid (CSF), serum and in CSF oligoclonal bands from nine patients with meningopolyneuritis Garin-Bujadoux-Bannwarth (MPN-GBB). All patients showed specific IgG and IgM antibodies in serum and CSF when incubated with a lysate of B. burgdorferi strain B 31. Specific antibody was detected in CSF but not in paired serum samples, indicating intrathecal synthesis. Investigation of the specificity of oligoclonal Ig in the CSF revealed oligoclonal bands with specificity for B. burgdorferi in one of the nine patients.
在9例加林-布雅杜-班瓦特脑膜多神经炎（MPN-GBB）患者的脑脊液（CSF）、血清及CSF寡克隆区带中，研究了免疫球蛋白（Ig）对伯氏疏螺旋体成分的特异性。所有患者的血清和CSF与伯氏疏螺旋体菌株B 31裂解物孵育时，均显示出特异性IgG和IgM抗体。在CSF中检测到特异性抗体，但配对血清样本中未检测到，表明存在鞘内合成。对CSF中寡克隆Ig特异性的研究显示，9例患者中有1例存在对伯氏疏螺旋体具有特异性的寡克隆区带。
