Olszewski W L, Lukomska B, Engeset A
Arch Immunol Ther Exp (Warsz). 1982;30(1-2):79-86.
The concentrations of C1 inactivator and C3b inactivator were measured in the peripheral lymph of leg of normal men and compared with the concentrations in serum. Both inactivators were found in lymph, however, in concentrations lower than in serum (lymph/serum ratio for C1INA 0.236, for C3bINA 0.238). The levels of C1INA proteins in lymph were higher than of C1q and C1s (p less than 0.05), and of C3bINA higher or equal to those of C3 and C3PA. This may indicate, that the relatively high concentrations of both inactivators in the extravascular space, as compared with complement component proteins, can play a role in the control of activation process of complement in the interstitium and also explain to some extent the observed low hemolytic activity of lymph C1 and C3.
测定了正常男性腿部外周淋巴中C1灭活剂和C3b灭活剂的浓度，并与血清中的浓度进行比较。在淋巴中均发现了这两种灭活剂，但其浓度低于血清（C1INA的淋巴/血清比值为0.236，C3bINA的淋巴/血清比值为0.238）。淋巴中C1INA蛋白水平高于C1q和C1s（p<0.05），C3bINA水平高于或等于C3和C3PA。这可能表明，与补体成分蛋白相比，血管外空间中这两种灭活剂的相对高浓度可在控制间质中补体激活过程中发挥作用，并且在一定程度上也解释了观察到的淋巴C1和C3的低溶血活性。
