Acheson E D, Pippard E C, Winter P D
Br J Cancer. 1982 Dec;46(6):940-6. doi: 10.1038/bjc.1982.305.
This paper reports a survey of nasal cancer in Northamptonshire during the period 1950-79. An increased risk of various histological types of nasal tumour has been observed within the footwear manufacturing industry, which seems to be limited to the minority of men and women exposed to the dust of leather soles and heels. In Northamptonshire this exposure has usually occurred in the preparation, press and finishing rooms of factories making boots and shoes by the welted process. This type of leather is tanned by treatment with vegetable extracts, not chrome salts. Although the population of workers involved has diminished over the period of the study there has been no evidence of a decline in incidence of these tumours within it.
本文报告了1950年至1979年期间对北安普敦郡鼻咽癌的一项调查。在制鞋行业中,已观察到各种组织学类型的鼻腔肿瘤风险增加,这种风险似乎仅限于少数接触皮革鞋底和鞋跟粉尘的男性和女性。在北安普敦郡,这种接触通常发生在采用沿条工艺制作靴子和鞋子的工厂的准备、压制和整理车间。这种皮革是用植物提取物而非铬盐鞣制的。尽管在研究期间,涉及的工人数量有所减少,但没有证据表明该群体中这些肿瘤的发病率有所下降。