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住院患者暴力行为与精神分裂症患者:危险相关事件与抗精神病药物水平之间的负相关关系。

Inpatient violence and the schizophrenic patient: an inverse correlation between danger-related events and neuroleptic levels.

作者信息

Yesavage J A

出版信息

Biol Psychiatry. 1982 Nov;17(11):1331-7.

PMID:7150681
Abstract

A correlational analysis of neuroleptic serum levels and measures of inpatient violence in 58 male schizophrenic patients is presented. Significant correlations were found between thiothixene (Navane) serum levels and several measures of inpatient violence including assault. The large variance noted with serum levels of neuroleptics on fixed doses may account for patients who have lower serum levels receiving less control of psychotic symptoms which may lead to violent behavior.

摘要

本文对58例男性精神分裂症患者的抗精神病药物血清水平与住院期间暴力行为的测量指标进行了相关性分析。发现硫利达嗪(甲硫达嗪)血清水平与包括攻击行为在内的多项住院期间暴力行为测量指标之间存在显著相关性。固定剂量的抗精神病药物血清水平存在较大差异,这可能解释了血清水平较低的患者对精神症状的控制较少,进而可能导致暴力行为。

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Inpatient violence and the schizophrenic patient: an inverse correlation between danger-related events and neuroleptic levels.住院患者暴力行为与精神分裂症患者:危险相关事件与抗精神病药物水平之间的负相关关系。
Biol Psychiatry. 1982 Nov;17(11):1331-7.
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