Gonvers J J, Fontolliet C, Boumghar M, Loup P, Anani P, Hofstetter J R
Schweiz Med Wochenschr. 1978 Dec 2;108(48):1899-901.
Benign liver cell tumors in young women are reported with increasing frequency. An association between benign tumors and oral contraceptive use was first suggested in 1973 by Janet Baum. During the past ten years we have observed 15 benign liver cell tumors, all of the focal nodular hyperplasia type. Ten of the 15 women were taking or had taken oral contraceptives. This association was found not to be statistically significant (0.06 greater than p greater than 0.05). We also diagnosed 2 liver cell carcinomas in women who had taken contraceptives.
年轻女性良性肝细胞肿瘤的报告频率日益增加。1973年珍妮特·鲍姆首次提出良性肿瘤与口服避孕药的使用之间存在关联。在过去十年中，我们观察到15例良性肝细胞肿瘤，均为局灶性结节性增生类型。15名女性中有10名正在服用或曾服用口服避孕药。发现这种关联在统计学上不显著（0.06＞p＞0.05）。我们还诊断出2例服用避孕药的女性患有肝细胞癌。
