Fleming P J, Levine M R, Goncalves A
Pediatr Res. 1982 Dec;16(12):1031-4. doi: 10.1203/00006450-198212000-00013.
Investigation of respiratory control requires an accurate measuring system which does not itself alter the pattern of respiration. We have used a transthoracic impedance pneumograph to investigate the effects of application of a face mask plus pneumotachograph or the face mask rim alone on tidal volume and respiratory frequency in 10 sleeping term infants aged 1-4 days. Application of the face mask rim led to a small but significant fall in respiratory frequency, 12% in quiet sleep (QS) and 17% in rapid eye movement (REM); with the application of the complete face mask plus pneumotachograph, changes were 10% and 14% in QS and REM, respectively. These changes were accompanied by rises in tidal volume of similar magnitude (15%, 11% in QS and 21%, 17% in REM, respectively). These results suggest that the change in respiratory pattern is due mainly to trigeminal stimulation rather than respiratory loading; thus, recordings obtained by methods utilising face masks cannot be considered to represent undisturbed respiration, for at least the first 15 min of recording.
呼吸控制的研究需要一个准确的测量系统，该系统本身不会改变呼吸模式。我们使用经胸阻抗呼吸描记器，研究了给10名1 - 4天大的足月睡眠婴儿佩戴面罩加呼吸流速计或仅佩戴面罩边缘对潮气量和呼吸频率的影响。佩戴面罩边缘导致呼吸频率小幅但显著下降，安静睡眠（QS）时下降12%，快速眼动（REM）睡眠时下降17%；佩戴完整面罩加呼吸流速计时，QS和REM睡眠时的变化分别为10%和14%。这些变化伴随着潮气量出现类似幅度的增加（QS睡眠时分别为15%、11%，REM睡眠时分别为21%、17%）。这些结果表明，呼吸模式的变化主要是由于三叉神经刺激而非呼吸负荷；因此，至少在记录的前15分钟内，使用面罩的方法所获得的记录不能被认为代表未受干扰的呼吸。
