Lopukhin Iu M, Sergienko V I, Kogan E M, Archakov A I, Belov N N
Kardiologiia. 1982 Dec;22(12):27-30.
Results of haemosorption with the use of activated carbon IGI in patients with different diseases of the liver are given. It is shown that along with the toxic metabolites the method serves to remove a considerable quantity of cholesterol. It is surmised that haemosorption can become an effective method of control of hypercholesterolemia in atherosclerosis and its complications. The results of stand tests of sorbents specific for cholesterol are presented. A sorbent, synthesized from a metal-containing polymer was used for haemosorption in experiments on rabbits with alimentary hypercholesterolemia. Single haemosorption lasting 30 min led to a two-fold decrease of the cholesterol level in the blood and to a two-fold decrease of the damaged area in the aorta 4 weeks after operation.
给出了使用IGI活性炭对不同肝脏疾病患者进行血液吸附的结果。结果表明，该方法除了能清除有毒代谢产物外，还能去除大量胆固醇。据推测，血液吸附可能成为控制动脉粥样硬化及其并发症中高胆固醇血症的有效方法。文中还展示了胆固醇特异性吸附剂的标准测试结果。一种由含金属聚合物合成的吸附剂被用于对患有饮食性高胆固醇血症的兔子进行血液吸附实验。单次持续30分钟的血液吸附导致术后4周时血液中胆固醇水平降低两倍，主动脉损伤区域减少两倍。
