Miller F S, Bunt-Milam A H, Kalina R E
Ophthalmology. 1982 Dec;89(12):1478-88. doi: 10.1016/s0161-6420(82)34613-8.
Advanced thioridazine retinopathy was observed clinically and histopathologically in a 61-year-old man with progressive, severe loss of vision who had received thioridazine in high dosages 18 years previously. The ocular fundi showed multiple confluent, nummular areas of hypopigmentation and choroidal atrophy posterior to the equator. Atrophy and disorganization of the photoreceptor outer segments appeared to be the initial degenerative event, followed by loss of the retinal pigment epithelium and choriocapillaris.
在一名61岁男性患者中，临床和组织病理学观察到晚期硫利达嗪视网膜病变。该患者视力进行性严重丧失，18年前曾接受过高剂量硫利达嗪治疗。眼底显示赤道后方有多个融合的钱币状色素减退区和脉络膜萎缩。光感受器外段的萎缩和结构紊乱似乎是最初的退行性病变，随后是视网膜色素上皮和脉络膜毛细血管的丧失。
